Give differences: Mendelian disorders and Chromosomal disorders.

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Mendelian disorders Chromosomal disorders
$(1)$ These are caused by an alteration or mutation in a single gene. $(1)$ These are caused by the absence,excess,or abnormal arrangement of one or more chromosomes.
$(2)$ They are transmitted to subsequent generations following Mendelian principles of inheritance. $(2)$ They are generally not transmitted as the affected individuals are often sterile.
$(3)$ They can be recessive or dominant in nature. $(3)$ These are typically associated with large-scale genomic changes and are often dominant in their phenotypic expression.
$(4)$ Examples: Colour blindness,Phenylketonuria,Haemophilia. $(4)$ Examples: Down's syndrome,Turner's syndrome,Klinefelter's syndrome.

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